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br Results and discussion The morphology and
2025-01-16
Results and discussion The morphology and structure of PBIT sale samples were observed using an SEM, as shown in Fig. 1. The length and thickness of the actin filaments were regulated with ABPs to mimic the various actins observed in cells. We prepared three types of F-actin with or without gelso
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br Acknowledgments We thank the anonymous reviewers for thei
2025-01-16
Acknowledgments We thank the anonymous reviewers for their constructive comments on the manuscript, and also thank Dr. Hans-U. Dahms for his comments on the manuscript. This work was supported by a grant from the National Research Foundation (2009-0071218) funded to Young-Mi Lee. This work was al
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The difficulty of characterizing nAChRs in the central nervo
2025-01-16
The difficulty of characterizing nAChRs in the central nervous system is also exemplified by early observations that nicotine caused no detectable effect when applied on a brain slice and it is only with the focal and high time resolution of more recent experiments that the effects of nicotinic neur
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Compound was synthesized by reacting amino methoxybenzoate w
2025-01-15
Compound 31 was synthesized by reacting 5-amino-2-methoxybenzoate (28) with ethanesulfonyl chloride in the presence of pyridine in DCM to give sulfonamide 29. Hydrolysis of 29 by aqueous sodium hydroxide afforded the gssg 30 which was converted to the acid chloride by heating in thionyl chloride. R
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The approach of enzymatically converting an
2025-01-15
The approach of enzymatically converting an analyte and detecting it by the resulting small pH changes near the reduced graphene oxide (rGO) surface has successfully been pursued in case of urea (Piccinini et al., 2017). Furthermore, this work reported that electrostatic layer-by-layer (LbL) assembl
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Serum concentrations of APP and
2025-01-15
Serum concentrations of APP and antioxidants of the 10 queens with pyometra before surgery (T0), at day two (T1) and at day 10 (T2) after ovariohysterectomy are presented in Fig. 1. Concentrations of SAA and Hp were significantly lower (P Discussion Acute phase protein responses were already desc
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br Results We set out to identify in
2025-01-15
Results We set out to identify in an unbiased manner a set of candidate “scaling factors” that might participate in transcription-dependent synaptic scaling up. The ex vivo slice and profiling studies were conducted on HsCt5 mice (described later) at postnatal day (P) 14 to P15, an age at which s
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The obtained results indicate that even when the impairment
2025-01-15
The obtained results indicate that even when the impairment of the same forms of memory are present, amnesia can develop in different ways. Impairment of memory reconsolidation in the conditioned food aversion model through both the serotonin receptor antagonist and the antagonist of NMDA glutamate
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Our studies also reveal the normal functional roles of
2025-01-14
Our studies also reveal the normal functional roles of the MIR. Interaction between the MIR loop and the N-terminal α helix nucleates conformational maturation of AChR subunits, thereby promoting assembly of mature AChRs [52], [55]. This interaction in homologous parts of all AChR subunits appears t
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br There are three types of HT receptors HT A
2025-01-14
There are three types of 5-HT2 receptors. 5-HT2A, 5-HT2B and 5-HT2C receptors Exhibit 46–50% overall sequence identity and couple preferentially to Gq/11 to increase inositol phosphates and cytosolic [Ca2+] and in agreement with their long known role in muscle contraction and stimulation in the br
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br Innate immune mechanisms that confront viral infection
2025-01-14
Innate immune mechanisms that confront viral infection Autophagy induction by virus sensing Antiviral xenophagy and virophagy The presence of viral particles within autophagosomal structures has been visualized in only rare instances. This is the case for HSV-1 when it is devoided of ICP34.
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cas9 mrna CORT induced hippocampal damage has been implicate
2025-01-14
CORT-induced hippocampal damage has been implicated in depression, aging and long-term glucocorticoid therapy. Therefore, finding a drug that can protect hippocampal neurons from the adverse effects of CORT could have significant clinical benefits. In this regard, we tested the potential protective
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Obesity is associated with chronic low grade
2025-01-14
Obesity is associated with chronic low-grade Endogenous opioid peptide resulting from increased M1 macrophage infiltration into adipose tissue, which can subsequently lead to the development of insulin resistance. Previously, we reported that LFE and FSB both reduced body weight gain in high fat di
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Rac1 functional domain Later on Wayner Burton Ingold
2025-01-14
Later on, Wayner, Burton, Ingold, Barclay, and Locke (1987) modified the method by using lipid to examine the ability of an antioxidant Rac1 functional domain protect against lipid peroxidation generated by azo-compound. It was later improved using β-phycoerythrin (β-PE) as a fluorescent probe, and
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CSF-1R The electrokinetic remediation technique is carried o
2025-01-14
The electrokinetic remediation technique is carried out with a low-level direct current, and the pollutants in soil can be transported and removed by the electric field [19]. This works well even in soil with low permeability via electro-osmotic flow and electro-migration [20]. The electrokinetic pr
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