• More recent studies have correlated sPLA V with alternative

  2019-07-15

  

  More recent studies have correlated sPLA2-V with alternative macrophage activation (M2) in human and murine macrophages [149,150]. sPLA2-V expression was induced during both human and mouse interleukin-4–mediated activation of macrophages in vitro, and its absence impaired macrophage activation in v

• Etomoxir is br Halogenases Enzymatic C H activation leading

  2019-07-15

  

  Halogenases Enzymatic C–H activation leading to halogenation is another emerging area in biocatalysis [55,56]. Incorporation of halogen atoms during medicinal chemistry eff ;orts is a well-established practice, presenting an effective means to control the molecule’s bioactivity and physicochemical

• Adding more pieces to the puzzle using a human

  2019-07-15

  

  Adding more pieces to the puzzle, using a human-to-animal crossover study, blood taken from healthy volunteers that underwent exercise was used as a dialysate to perfuse a rabbit heart in a Langendorff model of MI [62]. Unprecedentedly, dialysate of plasma from exercised humans reduced infarct size

• The component E of PDHc PDHc E

  2019-07-15

  

  The component E1 of PDHc (PDHc-E1) catalyzes the first step of multistep processes, using thiamine diphosphate (ThDP) and Mg2+ as cofactors.15, 16 Especially, this PDHc-E1 catalyzed process is a rate limiting step among multistep processes. Accordingly, the PDHc should be inactive by inhibiting the

• Many processes can lead to changes in soil P

  2019-07-13

  Many processes can lead to changes in soil P pools over time. Plant-available P (when measured as DGT P) decreased over time for the INORG-P treatment (Fig. 1a).

• Confirmation of the presence of H PPase genes in

  2019-07-12

  Confirmation of the presence of H+-PPase genes in the genomes of the different protists tested was obtained by Southern blot analyses using the PCR-amplified DNA fragments as probes (Fig. 3).

• Introduction In mammals there are

  2019-07-11

  Introduction In mammals there are ten known isoforms of the enzyme diacylglycerol kinase (DGK), as well as gene splice variants.

• To determine direct DDR binding partners and

  2019-07-10

  To determine direct DDR1-binding partners and to further connect to Akt and mTOR signaling, we performed mass spectrometry on DDR1 immunoprecipitates and found various candidates of the Akt and mTOR pathway such as LARP1 (La-related protein 1) and RPS6 (40S ribosomal protein S6/ S6).

• Epitope analyses of AT AA and ET AA indicate that

  2019-07-09

  Epitope analyses of AT1-AA and ET-AA indicate that the AG-18 of both autoantibodies are located at the second extracelluar loop of both receptors. The specific epitopes for both autoantibodies are similar to what was reported previously in a cohort of patients from Brazil [6] and for AT1-AA also from North America [20], and European patients [5].

• Method Results Discussion In this cross sectional

  2019-07-08

  Method Results Discussion In this cross-sectional study, we investigated the relationship between the COMT ValMet polymorphism and age on regional cortical thickness in healthy adults across the lifespan.

• The causes of POD are complex and not entirely

  2019-07-05

  The causes of POD are complex, and not entirely clear.

• Several single nucleotide polymorphisms SNPs in humans

  2019-07-04

  Several single nucleotide polymorphisms (SNPs) in humans affect CYP3A expression and activity (Lamba et al., 2002).

• Accumulating evidence suggests that certain

  2019-07-03

  Accumulating evidence suggests that certain abnormal emotional traits, such as impulsive aggression and cluster B personality, are associated with suicidal behaviors (Currier and Mann, 2008, Mann et al., 2009, Rujescu et al., 2007, Turecki, 2005).

• The small intestine in addition to

  2019-07-02

  The small intestine, in addition to its primary role of absorption, has the ability to metabolize drugs and other xenobiotics through phase 1 and phase 11 metabolisms [25] since almost all the cytochrome P450 Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] present in the liver are also present in the small intestine although, in lower concentrations.

• In LPS treated BV cells we found that the upregulated

  2019-07-01

  In LPS-treated BV-2 cells, we found that the upregulated CysLT2R was translocated into the nucleus.

14975 records 998/999 page Previous Next First page 上5页 996997998999