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Expression of DDR in endothelial cells has been
2019-10-17

Expression of DDR1 in endothelial cells has been previously described in human corneal blood vessels, and more recently, in murine atherosclerotic plaques (Franco et al., 2008, Mohan et al., 2001). So far, there is a lack of evidence for DDR1 expression in endothelial cells in the mouse notch signal
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The objective of the present study was to investigate the
2019-10-17

The objective of the present study was to investigate the role of the CRF system in the neuroadaptations associated with nicotine dependence. To this aim, the regulation of the gene expression of CRF and its receptors was assessed in ana cas mass regions belonging to the reward pathway using a mode
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br Results br Discussion Drug resistance poses the
2019-10-17

Results Discussion Drug resistance poses the greatest hurdle of achieving high efficacy with AADs in cancer patients. AAD-treated cancer patients often encounter intrinsic and evasive drug resistance that diminishes the therapeutic efficacy to only minor survival benefits in most cancer types.
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This work started from the standard version
2019-10-17

This work started from the standard version of the CPA model [17] and investigated its known weaknesses: 1) not meeting the defined critical temperature, 2) missing the temperature dependence of pure component saturated liquid densities, 3) using an α function in the cubic term that can provide unre
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Notochord is a transient structure differentiating at early
2019-10-17

Notochord is a transient structure differentiating at early stage during embryogenesis that is at the origin of vertebral bodies in all vertebrates. In zebrafish, it is composed of vacuolated inhibitor chemistry clinical surrounded by a unique ECM structure improperly called notochordal BM. As in c
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CARIPORIDE The P H activity and the large number of
2019-10-17

The P4H activity and the large number of 4-Hyp residues that are formed, amounting to half of all the Pro residues or 10% of all residues, have been identified as having a clear role in the structure and chemistry of the triple helix [3]. The role of the rare 3-Hyp residues is less clear and is stil
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Several studies suggest that the beneficial metabolic effect
2019-10-17

Several studies suggest that the beneficial metabolic effects of adiponectin in humans are primarily mediated by its HMW isoform. Increases in the ratio of HMW to total adiponectin, but not the total adiponectin level, correlated well with improved 5-EdU sensitivity during treatment with the insulin
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All tested antibodies exhibited positive
2019-10-17

All tested gap-27 exhibited positive immunoreactivity in NSCLC tumors, with N’-epitope being the less expressed (both as overall positivity and number of positive cases, or intensity combined with number of positive cells, as provided by H-Score. This result is in accordance with previous studies [
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In the present study we investigated the
2019-10-17

In the present study, we investigated the role of EP1R after ICH and its mechanism of action. We hypothesized that EP1R activation aggravates ICH injury but that its blockade reduces injury through the Src kinases and the MMP-9 signaling pathway. To test this hypothesis, we examined the effects of s
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br Conclusion In summary a novel
2019-10-16

Conclusion In summary, a novel and label-free fluorescence assay was developed for detection of Cu2+ and galactose oxidase using water-dispersible homogenous alloyed CdZnTeS QDs. The CdZnTeS QDs were firstly synthesized via a simple one-pot hydrothermal route using DMSA as the S source, surface l
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br Experimental Procedures br Acknowledgments We
2019-10-16

Experimental Procedures Acknowledgments We thank R. Brink for providing HEL2x, M. Tanaka for CD169DTR mice, R. Lathe for making Cyp7b1+/− mice available, and M. Barnes and A. Reboldi for comments on the manuscript. T.Y. is an Irvington Institute Postdoctoral Fellow at the Cancer Research Insti
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br Introduction In most of the angiosperms
2019-10-16

Introduction In most of the angiosperms, sexual reproduction requires a process called double fertilization where the specialized cell division called meiosis produces haploid gametes combine to form diploid (2n) embryo. In hoechst 33342 to this, apomixis, naturally occurs in at least 400 plant
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br Materials and Methods br Acknowledgements br Introduction
2019-10-16

Materials and Methods Acknowledgements Introduction Collagen fibrillogenesis, the assembly of collagen fibers, is a critical process in the development, maturation, and repair of mammalian tissue. Alterations in the structure and amount of deposited collagen fibers can greatly alter the int
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br Conclusions This study showed that in
2019-10-16

Conclusions This study showed that in EOC cells, tyrosine kinase receptor DDR1 was expressed mainly in EOC ONX0914 mass with an Epithelial phenotype. The repressed expression of DDR1 in EOC cells with Mesenchymal phenotype could be due to the higher CpG methylation levels observed at the promote
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In Hevea brasiliensis both the soluble PPase
2019-10-16

In Hevea brasiliensis, both the soluble PPase and the membrane-bound V-PPase are present in the latex; the soluble PPase is in the C-serum (cytosol) of the latex [6] and the V-PPase is on the tonoplast of the lutoid, a special vacuole in the laticifers of rubber trees [7]. The V-PPase on the lutoid
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